Member of Yale faculty since 1962.
Not accepting lab members at this time.
Contact Info
Research
Most of my current work deals with the relationship between structure, conformation and optical rotation. Compounds of potential interest are prepared and converted to the chiral form via chemical resolution, kinetic resolution and related methods. The chiroptical properties are measured, and in collaboration with Prof. Vaccaro, the optical rotation is also determined in the gas phase. These experimental studies are supported by high level ab initio calculations.
Education
B.S. Massachusetts Institute of Technology, 1948
Ph.D. Columbia University, 1950
Honors
- A. P. Sloan Foundation Fellow, 1958
- Guggenheim Fellow, 1961
- Member, National Academy of Sciences, 1967
- Member, American Academy of Arts and Sciences, 1968
- Fellow, American Association of Arts and Sciences 1972
- J. F. Norris Award in Physical Organic Chemistry, 1974
- Cope Scholar, 1986
- Arthur C. Cope Award, 1988
- Pauling Meda, 1992
Recent Publications
Wiberg, K. B. Relationship between Rotational Barriers and Charge Shifts,” J. Org. Chem., 2019, 84, 475.
Wiberg, K. B.; Rablen, P. R. Increase in Strain Energy during the Conversion of [4.4.4.5] Fenestrane to [4.4.4.4]Fenestrane: a Method for Estimating the Heats of Formations of Hydrocarbons and Their 142 Derivatives from ab Initio Energies. J. Org. Chem., 2020, 85, 4981-4987.476.
Labet, K. M.; Cox, J.B.; Litz, L.; Jackson, A. C.; Yruegas, S.; Wiberg, K.B.; Wood, J. L.,Total Synthesis of (=/-)-Phyallantidine: Development and Mechanistic Evaluation of Ring Expansion for Installation of Embedded Nitrogen-Oxygen Bonds. Ange. Chem. Int. Ed., 2020, 59, 9757-9766.
Wiberg, K. B,; Rablen, P. R. Re-Examination of Some Carbocatins:, Structures, Energies and Charge Distributions. J. Org. Chem., 2020, 85, 11471-11479.
Wiberg, K.B. Halogen-Halogen Nonbonded Interactions. ACS Omega, 2021, 6, 15199-15204.