Join Yale Chemistry for a Biochemistry Seminar with Ellinor Haglund, Assistant Professor, Department of Chemistry, College of Natural Sciences, University of Hawaiʻi at Mānoa.
Title: The Folding and Function of Proteins with a Complex Topology
Professor Haglund’s work is focused on a combination of molecular dynamics simulations and in vitro biophysical characterization of the folding and function of proteins with a so-called Pierced Lasso Topology (PLT). A PLT is a “knot-like” topology where a covalent loop is formed in the protein backbone and part of the amino acid chain threads through this region. More than 600 proteins with PLTs have been discovered to date, represented in all kingdoms of life.
This seminar is generously sponsored by the Mrs. Hepsa Ely Silliman Memorial Fund.