Caitlin Davis
Member of Yale faculty since 2020
Research Interests
Research
The Davis lab uses experiments at multiple scales, from in vitro to single cell to whole organism, to study fundamental and applied problems at the intersection of chemistry, physics, and biology. A common theme of our research is the development of quantitative spectroscopic imaging techniques to investigate the relationship between function and dynamics in biological systems. This quantitative biophysical approach will be used to address kinetic questions that require characterization in the complex, heterogeneous environment of the cell.
Education
B.S. University of Michigan, 2007
Ph.D. Emory University, 2015
CPLC Postdoctoral Fellow, University of Illinois at Urbana-Champaign, 2015-2019
Honors
Beckman Young Investigator, 2024-2028
National Science Foundation Faculty Early Career Development (CAREER) Award, 2024-2029
Hevolution/AFAR New Investigator Awards in Aging Biology and Geoscience Research, 2024-2026
Scialog Fellow, 2019-2021
Center for the Physics of Living Cells Postdoctoral Fellowship, 2015-2019
Recent Publications
Castillo, H.B. †; Shuster, S.O. †; Tarekegn, L.H.; Davis, C.M. “Oleic acid differentially affects lipid droplet storage of de novo synthesized lipids in hepatocytes and adipocytes,” Chem. Comm. 2024, 60: 3138-3141. DOI: 10.1039/D3CC04829B
Knab, E.; Davis, C.M. “Chemical interactions modulate l6-85 stability in cells,” Protein Sci. 2023, 32 (7): e4698. DOI: 10.1002/pro.4698
Shuster, S.O.; Burke, M.J.; Davis, C.M. “Spatiotemporal heterogeneity of de novo lipogenesis in fixed and living single cells,” J. Phys. Chem. B, 2023, 127 (13): 2918-2926. DOI: 10.1021/acs.jpcb.2c08812
Yoo, H.; Davis, C.M. “An in vitro cytomimetic of in-cell RNA folding,” ChemBioChem. 2022, 23 (20): e202200406. DOI: 10.1002/cbic.202200406
Feng, R.; Gruebele, M.*; Davis, C.M.* “Quantifying protein dynamics and stability in a living organism,” Nat. Commun. 2019, 10, 1179. DOI: 10.1038/s41467-019-09088-y