We are recruiting on behalf of a number of departments. Please see the open job descriptions here.
Investigator, Drug Substance Development (Upper Providence, PA) GSK is seeking a proactive chemist to join Drug Substance Development at our US R&D Hub located in Upper Providence, PA. Our Drug Substance Development group supports the small molecule portfolio in GSK Pharma R&D with an inter-disciplinary team of process chemists, chemical engineers, materials scientists, and synthetic biochemists by developing the synthetic routes and associated manufacturing processes that turn those molecules into medicines. Through our network of 86 manufacturing sites, each year we produce nearly 4 billion packs of medicine, and we are committed to widening access to our products so that more people may benefit. A successful applicant will have an excellent practical and theoretical understanding of synthetic organic chemistry or a relevant technology and can design and execute high quality, thoughtful experimentation, while making significant contributions both independently and as a member of a team.
Basic qualifications
Scientific:
• Ph.D. in Chemistry or equivalent industrial experience
• Expertise in state-of-the art synthetic organic chemistry
• Excellent problem-solving skills
• Scientific record demonstrating excellence in chemistry (e.g., publications, patents, or presentations)
• Experience in independent planning and execution of experiments
• Experience in independent interpretation of data from experiments and using it to make meaningful conclusions/decisions regarding the direction of future experimentation
Investigator, Biocatalysis (Upper Providence, PA) GSK is a world leading research-based pharmaceutical company that combines both individual talent & technical resources to create a platform for the delivery of strong growth in a rapidly changing healthcare market. Our mission is to improve the quality of human life by enabling people to do more, feel better, & live longer.
An exciting opportunity has arisen in GSK’s Enzyme Evolution and Biocatalysis group. The primary focus of this role is to support the discovery and implementation of novel enzyme-based chemistry at GSK. This role is fast-paced and dynamic, you will thrive in this environment if you are able to effectively manage multiple priorities, communicate your recommendations clearly, and enjoy working in teams.
Basic qualifications:
• Ph.D. in Chemistry, Biochemistry, Chemical Biology, or related field with 1-2 years relevant experience.
• Experience in the discovery and development of organic and biocatalytic reactions.
• Experience in enzyme characterization including a background in mechanistic and kinetic studies of enzymatic reactions (Vmax, Km, product inhibition, substrate inhibition, cofactors, redox chemistry).
• Demonstrated ability to work in multi-disciplinary teams, with excellent interpersonal, organizational, and communication skills.