Thesis Defense: James Breton

Please join Yale Chemistry for a thesis seminar with James Breton, Johnson Lab.

Title: Harnessing Commercial High Resolution Mass Spectrometry (HRMS) & Cryogenic Ion Vibrational Predissociation (CIVP) Spectroscopy for Structural Characterization of [Co2Ln]2+ Complexes

Summary:  This dissertation describes how a commercial instrument (in this case the Thermo-Fisher Q-Exactive high resolution Orbitrap mass spectrometer) can be adapted to enable structural characterization of analytes by analysis of their vibrational spectra obtained at cryogenic temperature. The main goal of this effort was to implement IR spectroscopy as a user-option that is integrated into the normal operation workflow without compromising any of the capabilities that are provided by the Q-Exactive for routine MS analysis. Exploiting the capabilities of this hybrid instrument, the structural characterization for a series of tri-metallic coordination complexes with one lanthanide center (Ln) sandwiched between two Co ions (hereafter denoted Co2Ln2+) was performed.